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In addition to these core symptoms, individuals with ASD frequently exhibit specific cognitive characteristics, including weak central coherence, hyper-systemization, a stick-to-the-sameness, and atypical sensory processing [1]

Specifically, we systematically dissect the multifaceted roles of lactate and lactylation through the lens of five distinct pathological pillars of PH: (1) aberrant proliferation of pulmonary artery smooth muscle cells (PASMCs), (2) dysregulated immune-inflammatory responses, (3) progressive pulmonary fibrosis, (4) abnormal vasoconstriction, and (5) PASMC ferroptosis

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