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However, physical injury, oxidative stress, mPTP opening, or BAX/BAK-mediated membrane permeabilization can trigger its release into the cytosol or extracellular space [32, 76]

Certain probiotic strains direct mucosal immune activity by inducing the secretion of key cytokines and B-cell growthpromoting factors, including interleukin-4 (IL-4), interleukin-5 (IL-5), and interleukin-13 (IL-13) (215, 244)

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Normally, Vnn1 is activated under starvation and fasting conditions to redirect CoA from peripheral tissues to the liver 48

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