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Wegovy works partly by slowing how quickly food leaves your stomach and by acting on appetite centres in the brain, so when those effects wear off, you may find yourself feeling hungry sooner after meals and thinking about food more than you did while on the medication

This partial agonist 8 is selective over other subtypes of PPAR, highly potent on both targets, and exhibits only slight toxicity (Merk et al., 2015)

Zepbound is administered as a subcutaneous injection once per week

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Liu J, Li L, Xie P, et al