In 2021, the GLP-1 market was valued at $16.53 billion, with a compound annual growth rate of 6.1%, with the market size (across T2D and obesity) projected to be over $24 billion by 2027
doi: 10.1016/S0140-6736(06)69705-5 49 DuarteA
223 Recently, a study found that alpha-TC1/6 cells can secrete GLP-1 under hyperglycemic, hyperlipidemic or inflammatory conditions during in vitro experiments, suggesting that this hormone may act locally to influence both islet alpha- and beta-cell behaviour during pathological conditions
Allostery and biased agonism at class B G Protein-Coupled receptors
During the initial period of using any new transdermal medication, patients may experience local skin reactions such as mild redness, itching, or irritation at the application site