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RXRalpha ablation in epidermal keratinocytes enhances UVR-induced DNA damage, apoptosis, and proliferation of keratinocytes and melanocytes

It is a synthetic version of the naturally occurring hormone Melanotan II, which is responsible for the production of melanin in the body

Etiologies 5.1

Withanolides (WS) may work by interacting with mediators of the inflammatory cell signaling pathway such as NF-B, signaling kinases, HSP90, Nrf2, and the inflammasome complex, although the exact processes underlying their anti-inflammatory effects are still poorly understood

Academic and government institutions currently lead the charge in launching new studies, showcasing a robust research ecosystem outside of purely commercial interests