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Exocytosis of synaptic vesicles (SV) containing neurotransmitters is initiated by Ca 2+ influx through voltage-gated Ca 2+ channels during excitation of the presynaptic bouton

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From day 2, cLip-1 (in-house, 10 mg per kg per day dissolved in 1 PBS containing 20% PEG400 and 5% Solutol HS15) or vehicle was intraperitoneally administered to the mice each day until the completion of the survival study

However, other studies have reported mixed results, with some trials showing no significant impact on TB relapse or culture conversion [77, 78]

But glutathione, through its support of the immune system, reduces this oxidative stress