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Supplementary information Supplementary Methods, Supplementary Figures 17 and Supplementary Tables 14 (PDF 598 kb) Rights and permissions About this article Cite this article Veeravalli, K., Boyd, D., Iverson, B

Meanwhile, GnRH antagonists such as relugolix and linzagolix rapidly suppress ovarian hormone production, leading to fibroid size reduction and symptom relief, with ongoing studies assessing their long-term safety and optimal dosing strategies

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Phase 2 trial data (NEJM, 2023) showed a mean body weight reduction of approximately 24% at the highest dose (12 mg weekly) over 48 weeks in adults without type 2 diabetes

Through this review, we aim to inform the readers of recent approaches for managing obesity and comparing their beneficial effects and efficacy on obesity and its long-term co-morbidities