Monitoring Schedule While on Spironolactone | Timepoint | What to Check | Why | |---|---|---| | Baseline (before starting) | BMP (potassium, sodium, creatinine, glucose), blood pressure | Establish safe starting point | | 4 to 6 weeks after starting or dose change | Repeat potassium and creatinine | Catch early hyperkalemia | | Every 3 months for first year | Potassium, blood pressure | Confirm stability | | Every 6 months thereafter | BMP, blood pressure | Ongoing safety surveillance | | After any episode of heavy drinking | Potassium, creatinine if symptomatic | Rule out acute electrolyte disturbance | What the Evidence Base Looks Like (And Where It Is Thin) No randomized controlled trial has specifically examined the interaction between alcohol and spironolactone in patients taking it for acne
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