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along with inhibitory effects of TNF-, TGF-, AP-1 and MAPK were also established [31,33]

N Engl J Med 2022;387:20516.ArticlePubMedPMC 11

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Later, Hornig and colleagues also suggested disturbed IL-1 signaling and autoimmunity-type patterns of immune activation while analyzing the cerebrospinal fluid in patients with atypical clinical characteristics (Hornig et al