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Therefore, refraining from alcohol helps to minimise these risks and ensures a safer and more effective treatment outcome

This observation, coupled with the added stability contributed by C-terminal amidation and the desire to increase the hydrophobicity of the peptide, led to the generation of a series of compounds with the structure, N-acyl-Tyr-Ile-(6) amino -hexanoic amide

Wegovy, also given once weekly, was first approved in 2021 for weight loss in adults with obesity

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