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Since PTX causes relaxation of smooth muscle mediated by cAMP, it is easily speculated that this agent increases mucosal blood flow by directly dilating vascular smooth muscle

The lack of data representative of diverse populations severely limits how new therapies will work in many populations that need treatment

Persistent activation of the HPA-axis increases the production of reactive oxygen species and pro-inflammatory cytokines throughout the body

Select heterozygous Keap1 mutations have a dominant-negative effect on wild-type Keap1 in vivo

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