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Nature medicine, 30(7), 20372048

He said theres also appears to be an effect in the brain, which has GLP-1 receptors, and in the lining of the blood vessels

While GLP-1 drugs promote fat loss, rapid weight reduction can lead to 1525% lean muscle mass loss

Since retatrutide is another GLP-1 agonist, it is likely to be unsuitable for those with a family history of thyroid cancer and anyone with multiple endocrine neoplasia syndrome type 2

This has led to renewed interest in understanding the safety of GIP/GIPR in humans