However, proposed mechanisms include disruption of microtubule function, potential impact on inflammation in the brain, interference with mitochondrial function, contribution to oxidative stress, and possible disruption of the blood-brain barrier
The long-term consequences of untreated low brain folatedevelopmental regression, speech impairment, seizures, and neuroinflammationcan be more severe than the risks associated with folate therapy
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Emadi A, Burns KH, Confer B, Borowitz MJ, Streiff MB (2008) Hematological manifestations of nephropathic cystinosis
The role of oxidative stress in some conditions that contribute to infertility Polycystic Ovarian Syndrome (PCOS): PCOS is an anovulatory cause of infertility in 6-10% of premenopausal women (Asuncin et al., 2000)