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[Adapted with permission from Naik P: Biochemistry, 3rd edition, Jaypee Brothers Medical Publishers (P) Ltd., 2009.] Excretion of Uric Acid Approximately two-thirds of uric acid is excreted by the kidneys, while the remaining one-third is excreted by intestinal uricolysis

First, these do usually decline with time as the body adjusts

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