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Elevated homocysteine in the blood, otherwise known as homocystinuria, if left untreated, can result in abnormal blood clotting, brittle bones, and nearsightedness, and increased risk of having a child with a neural tube defect (spina bifida)

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This activation is characterized by a predominance of T helper 2 (TH2) lymphocytes, innate lymphoid cells type 2 (ILC2) and eosinophils

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doi:10.1590/S0042-96861999000900007 (archival DOI reference) Hope J