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The most common complaints were nausea (55% versus 12.6% with placebo), constipation (30.7% versus 11.6%), and vomiting (26.1% versus 4.1%)

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In clinical trials, prophylactic use of carvedilol in cancer patients receiving anthracycline therapy has shown protective effects on left ventricular systolic function [158]

Westermark P, Sletten K, Johansson B, Cornwell GG