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Chronic hyperglycemia and insulin resistance: Increase oxidative stress Deplete glutathione Drive hepatic fat accumulation Elevated GGT frequently precedes the diagnosis of type 2 diabetes

There are some limitations since the current study is a review that focuses on SalB s involvement in fibrosis in various organs

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Transglutaminase 2 (Tgm2) covalently cross-links IB, further promoting NF-B nuclear translocation and enhancing the expression of phosphorylated p53 and p21

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