In clinical trials, such as SURMOUNT-1, participants on the maximum dose experienced significant weight loss
These findings are consistent with previous reports showing that exposed hydrophobic surfaces on amyloidogenic aggregates mediate aberrant interactions with essential cellular proteins, leading to their sequestration and functional impairment 81
The researchers also noted that the findings do not represent the views of the Department of Veterans Affairs or the U.S
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The trial outcomes demonstrated that 28 weeks after beginning the medication, individuals on the drug lost an average of 13% of their body weight, while those on the placebo gained 1.5%
