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Tomas FM, Knowles SE, Owens PC, Chandler CS, Francis GL, Read LC, Ballard FJ

Growth Hormone Activated the Janus Kinase 2 Gene (Jak2) in BPC 157-Treated Tendon Fibroblasts Through the JAK-STAT signaling pathway, growth hormone can exert the growth-stimulating effects on different tissues

Researchers comment that a single introduction of the peptide may upregulate growth hormone production by somatotrophs for prolonged periods of time, thus apparently contributing to an overall increase in [growth hormone] secretion by 46% and also potentially upregulating its main anabolic mediator insulin-like growth factor-1 (IGF-1) by 45% on average

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