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It is an intracellular metabolic-enzyme modulator, which is why its research read-outs are things like NAD+ levels and adipocyte gene expression, not how full you feel. That mechanistic distinction is the single most important thing to understand before looking at any dose number

Consider intramuscular vitamin B 12 injections instead of oral replacement for suspected or confirmed vitamin B 12 deficiency caused by diet if: The person has another condition that may deteriorate rapidly and have a major effect on their quality of life (for example, a neurological or hematological condition such as ataxia or anemia)

[3] Whilst Mounjaro itself does not directly cause B12 deficiency, the dietary changes and reduced food intake associated with its use could theoretically contribute to suboptimal nutrient intake

Understanding these factors can help individuals make informed decisions about their B12 injection options and find the most cost-effective solution for their needs

[35] Does a perioperative 8 mg dose raise infection risk