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Safe GLP-1 Use: Monitoring and Prevention Strategies Starting GLP-1 therapy at the lowest effective dose allows your digestive system to adapt gradually while minimizing gastrointestinal disruption

& Dvorak, J

Maxwell, L

More recently, GLP-1 receptor agonists and GLP-1R/GIPR dual-agonists have been introduced as injectable therapies for T2D, which potentiates endogenous glucose-induced insulin secretion and slows gastric emptying for improved glycaemic control, as well as decreases appetite and food intake that consequently reduces body weight and further improves metabolic homeostasis

Persistent fatigue despite adequate sleep and nutrition suggests potential underdosing or inadequate caloric intake