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Rather than raising NAD+ systemically (as NMN or NR supplementation does), NNMT inhibition preserves NAD+ specifically in the tissue where metabolic dysfunction is most pronounced a precision approach that appeals to researchers studying tissue-specific metabolic regulation

Studies show pp 332 effects on fat oxidation and inflammation make it useful for obesity, diabetes and fatty liver disease research

By supporting metabolic processes, B-12 injections may assist in weight management for some individuals