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The authors reported that in obese mice, daily AOD-9604 administration over 14 days produced significant reductions in body weight gain, decreases in adipose tissue mass, and increases in fat oxidation, with effect sizes comparable to those of full-length human growth hormone [1]

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What the clinical evidence shows Phase 2 monotherapy trials: cagrilintide alone The Phase 2 clinical trial for cagrilintide monotherapy was published in The Lancet in 2021