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the cascade of issues attached to the drugs was similarly unknown

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The fragment bovine GIP(4-42) was a partial agonist of the rat GIP receptor, concluding that N-terminal truncation of GIP alters its pharmacological properties from full agonist to partial agonist (59)

As an upstream event of ferroptosis, autophagy activation can induce ferroptosis through different mechanisms, including NCOA4-mediated ferritin autophagy [95], RAB7A-mediated lipid autophagy [96], ARNTL-mediated biological clock protein autophagy [97], and BECN1-mediated System X c inhibition [64]