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A biomarker qualification data submission released by the Predictive Safety Testing Consortium (PSTC) in 2009 included urinary kidney injury molecule-1 (KIM-1), urinary trefoil factor 3 (TFF-3), urinary beta-2 microglobulin (B2 M), urinary cystatin C (CysC), urinary albumin (uALB), urinary total protein (uTP), and urinary clusterin (CLU) as emerging biomarkers to study xenobiotic-induced kidney injury in rat (Dieterle et al

It may potentially help balance autoimmune conditions and help to improve survival in severe infections like sepsis

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They address the root physiological drivers of weight gain rather than just the symptoms