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In addition, GLP-1R agonists are known to decrease food intake and produce nausea/emesis in both drug-nave rodents and humans 4,20,29,30

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Once in the brain, ALC supports the production and activity of acetylcholine, a neurotransmitter involved in memory, focus, and overall cognitive function.* It also supports mitochondrial function in brain cells, contributing to the same energy production pathway that CoQ10 supports throughout the rest of the body.*

Patients should be counseled about the risk of hypoglycemia, particularly if taking concomitant insulin or sulfonylureas, though tirzepatide's glucose-dependent mechanism reduces this risk compared to older diabetes medications

All participants received guidance from a board certified obesity physician on proper medication use, resistance training, and adequate protein intake