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Abbreviations AE: adverse events ADA: American Diabetes Association CI: confidence interval CKD: chronic kidney disease CV: cardiovascular CVD: cardiovascular disease ETD: estimated treatment difference GLP-1RA: glucagon-like peptide-1 receptor agonist HR: hazard ratio MACE: major adverse cardiac event MI: myocardial infarction T2D: type 2 diabetes References American Diabetes Association

This is due to oxidative stress on skin cells and diminished production of new skin cells