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Clinical indications for intradiscal injection of MSCs are (a) treatment of discogenic pain without severe compression and/or neurologic deficits and (b) treatment of the adjacent degenerated discs during decompressive spinal surgery

Upon reception of a signal to migrate such as chemical mediators called chemokines present near the edge of the wound the bound pool of actin monomers becomes immediately available to form actin filaments in the lamellipodium and filopodia of migrating cells

doi: 10.1111/jnc.15239 32

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