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Moreover, it can initiate lipid peroxidation [59], disrupting cell membrane integrity and impairing cellular signaling and membrane function [60]

The activated GLP-1 receptors trigger the pancreas to release more insulin in response to high blood sugar (after meals) and simultaneously signal the liver to produce less glucagon , a hormone that raises blood sugar

Philosophical Transactions of the Royal Society of London Series B, Biol Sci 123, 71170

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Emerging Therapies and Expanding Potential The research agenda just outlined assumes a relatively stable therapeutic landscape, one in which the primary task is generating better evidence for the combinations already in use