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MECHANISM CATEGORIES SAFETY Side effects Generally well-tolerated in trials at the doses tested Injection-site reactions Known interactions Not characterized in Phase 3 Contraindications Pregnancy/lactation (unstudied) REGULATORY STATUS FDA Not FDA-approved as a drug

Others worried about the potential long-term risks of GLP-1s, which could require lifelong use given that weight usually returns when treatment ends

Long-term use also raises concerns around muscle loss, nutritional balance, and weight regain after discontinuation

Research shows that people with fibromyalgia often have low levels of several of these key nutrients

Paoloni may suggest taking an over-the-counter painkiller such as ibuprofen before your appointment