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Clinical Evidence Behind Semaglutide for Weight Loss The STEP (Semaglutide Treatment Effect in People with obesity) trials demonstrated that semaglutide produces average weight loss of 15% body weight over 68 weeks in non-diabetic adults, significantly outperforming diet and exercise alone

Vomiting : Along with nausea, some people may throw up

But there is a parallel conversation building in the longevity and geroscience literature that, if it pans out the way its early signals suggest, will eventually swallow the obesity framing entirely

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GLP-1 stands for glucagon-like peptide-1 , which is a natural hormone your gut makes after you eat