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The efficacy and safety of tirzepatide, with a special focus on cardiovascular safety, were investigated in the 52-week SURPASS-4 trial testing tirzepatide versus insulin glargine in adults with T2D and a high cardiovascular risk under inadequate glycemic control at baseline on one to three oral glucose-lowering medications (metformin, sulfonylurea, SGLT-2 inhibitor) (54, 74)

Furthermore, a more complex antioxidant mixture, containing CoQ, LC, -tocopherol and selenium was shown to decrease DNA damage in the liver of fumonisin B1-treated rats [150]

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Glutathione plays a crucial role in a detoxification system that is fundamental in plants, mammals, and fungi (3)