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Mechanism of Action Binds the IGF-1 receptor (IGF-1R) with reduced affinity for IGF-binding proteins, leading to prolonged activation of the PI3K/Akt and MAPK/ERK pathways that promote cell proliferation, differentiation, and inhibition of apoptosis

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CTA For CTA, mice were housed in cages that permitted AL access to water from two bottles side by side for at least 5 days before training and experimentation

Noelting et al., 2022