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The starting dose of 0.25 mg once weekly for the first four weeks is primarily intended to improve gastrointestinal tolerability rather than provide maximum therapeutic benefit

For example, many cases of acute diarrhea in a well cat can resolve with limited or no intervention, and so do not require a precise diagnosis

However, the activation of STAT3 signaling stimulates a negative feedback response through the induction of SOCS factors which not only inhibit the activity of insulin/IGF-1 receptors but also that of many cytokine receptors

While there are conventional treatments for feline hyperthyroidism, natural treatments are also effective