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It could have heavy metal contamination

For example, mice fed a high-fat diet for 21 days have both lipid and protein compositional changes in cellular plasma membranes that result in an impaired capacity for oxidative phosphorylation, increased reactive oxygen species (ROS) production, hepatosteatosis and insulin resistance (Shama et al., 2023)

But foods that fill you up and keep you satisfiedparticularly, protein, fat, and fibertrigger a greater release of GLP-1

In retatrutide, the GLP-1 and GIP components offset this effect, keeping blood sugar stable while still capturing glucagon's fat-burning benefits (Jastreboff et al., NEJM 2023)

What I found was not so amazing