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Deterioration of CD was classified according to the CD activity index (CDAI) (34), which is a composite scoring system based on selected clinical symptoms, such as the number of liquid stools, the severity of abdominal pain, general well-being, extraintestinal CD manifestations, abdominal mass, use of antidiarrheal drugs, as well as haematocrit and body weight

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Furthermore, intravenous glutathione (12 injections of 1,200 mg) showed no benefit for skin lightening compared to placebo in a Pakistani study (Zubair et al., J Pakistan Assoc Dermatol, 2016) [64]

Deuterated polyunsaturated fatty acids inhibit photoirradiation-induced lipid peroxidation in lipid bilayers