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PMID: 29155147): 5-Amino-1MQ showed NNMT selectivity with IC50 of 1.2 microM Reduced body weight and white adipose mass in diet-induced obese mice over 11 days No effect on food intake, suggesting metabolic rather than appetitive mechanism Nicotinamide N-methyltransferase inhibition mimics and boosts exercise-mediated improvements in muscle function in aged mice , published in Scientific Reports (Dimet-Wiley AL et al., 2024

Synonyms IGF-1 LR3 Long R3 IGF-1 Recombinant IGF-1 Analog Insulin-Like Growth Factor-1 Long Arg3 Research Areas IGF-1 LR3 is utilized in pre-clinical research models across the following areas: Cellular Growth & Proliferation Research: Investigating how IGF-1 receptor activation influences cellular expansion, replication signals, and protein synthesis pathways

There is a cutoff limit in diameter between a blastomere and a small anucleate fragment

doi: 10.1186/1471-230X-11-7 109

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