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All three were able to be co-cultured with primary hGEC from the same donor as hpPOD inside the GOAC, although hiPOD evidenced a less organized nephrin distribution, lower secretion of matrix proteins, such as collagen IV and laminin, and lower efficiency of permselectivity, which exalts the relevance of shifting away from using cell lines in OoC models

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Gastroenterology (2013) 145:158165.e2

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Liposomal and acetylated formulations may enhance absorption compared to standard oral tablets