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The drug was used in a double-blind, randomised, placebo-controlled trial including 526 adult participants with type 2 diabetes across China, India, Japan, Mexico, and the United States

Steady weight change : One to two pounds per week, or measurable changes in waist circumference

Thiazolidinediones: Single-dose pharmacokinetics of rosiglitazone was not meaningfully altered in subjects receiving multiple daily doses of sitagliptin, indicating that sitagliptin is not an inhibitor of CYP2C8-mediated metabolism

This medication is 94% similar to the natural GLP-1 hormone and, just like the natural version, it binds to GLP-1 receptors in your pancreas and other organs

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