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Nevertheless, translating these findings to human populations requires caution, as metabolic responses can differ substantially between species

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It is often discovered by the patient, who finds a fullness of the neck or a new lump while self-examining because of a vague discomfort in the neck

While the chemically induced models of PD, MPTP and 6-OHDA, provide valuable insight into the oxidative stress-related mechanisms of dopaminergic neuron loss in vivo , they do not fully recapitulate PD neuropathology with -syn aggregation (Meredith and Rademacher, 2011

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