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We were designed to survive in an environment in which we were highly active and had much less access to food (and no processed foods) while our modern life is based on processed foods & is highly sedentary

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Cardiovascular data on endpoints like MACE-3 or MACE-4 are presently not available yet, but an early meta-analysis demonstrated at least cardiovascular safety in patients with T2D treated with tirzepatide (78, 79)