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HGF is a potent neurotrophic factor that promotes neurogenesis and has been shown to have neuroprotective effects in neurodegenerative diseases (reviewed in: 37 )

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[4] [5] Patients are advised to report persistent abdominal pain, jaundice, or signs of severe allergic reactions immediately

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The Shank3-mutant mouse model is one of the most commonly used models to study epigenetic enzymes, and it was found that using histone methyltransferase inhibitors and histone acetylase inhibitors alone 520,521,522 or in combination 523 can both significantly improve NMDA dysfunction and social interactions in Shank3-mutant mice

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