The Ozempic prescribing information includes a warning about acute kidney injury and worsening of existing kidney problems, and states that "a majority of the reported events occurred in patients who had experienced nausea, vomiting, diarrhea, or dehydration." The same label tells doctors to counsel patients "of the potential risk of dehydration due to gastrointestinal adverse reactions and take precautions to avoid fluid depletion." The Mounjaro label carries the same class warning and advises doctors to "monitor renal function in patients reporting adverse reactions to MOUNJARO that could lead to volume depletion." It helps to keep this in perspective
doi: 10.1038/nrendo.2009.213
Research suggests it may help support: Healthy blood sugar metabolism Insulin sensitivity Carbohydrate handling Its naturally bitter compounds may also help reduce sweet cravings
Liraglutide (daily injectable) Dosing frequency: Once daily, same time each day Half-life: approximately 13 hours Peak concentration: 8 to 12 hours after injection Recommended timing approach: Because of the short half-life, time of day matters significantly more for liraglutide than for weekly formulations
Thorpe said a more permanent solution would be passage of a bill called the Treat and Reduce Obesity Act, which would lift Medicare's long-standing ban on coverage of obesity drugs
