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Description

Therefore, PLP dysfunction can lead to serious central nervous system disorders such as seizures [5]

Hypogonadotropic hypogonadism may be related to genetic mutations, medical conditions, eating disorders, or drugs that affect hypothalamic or pituitary function

These symptoms frequently manifest during the initial treatment phase, affecting approximately 50% to 60% of patients [8], but they generally diminish over time, with their occurrence being dose-dependent