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www.ars.usda.gov/Services/docs.htm?docid=25102 Duke, J

demonstrated that increased expression of DNA methyltransferases (DNMTs) leads to hypermethylation of the GPX4 promoter in osteoblasts, contributing to ferroptosis and osteoporosis (44)

Other metabolites, such as indole, abundant in the small intestine, furthermore modulate the release of glucagon-like peptide-1 (GLP-1), a crucial hormone in glucose metabolism 35

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Mechanism: Multi-System Weight Loss Semaglutide is a modified analog of human GLP-1, the incretin hormone released by intestinal L-cells after eating