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Patients who are pregnant or planning to become pregnant should inform their healthcare provider

According to the FDA, approximately 70% of adults in the United States are either overweight or obese

This becomes critical in the presence of pathogenic variants of any type (phenotype-related, secondary, or incidental), where therapeutic options may be limited or absent

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Lipid peroxidation transpires when reactive oxygen species (ROS) target polyunsaturated fatty acids (PUFAs) inside cell membranes, resulting in the production of bioactive aldehydes such as malondialdehyde (MDA) and 4-hydroxy-2-nonenal (HNE), which may conjugate with cellular macromolecules, impairing their functionality