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Timing Follow-up Marker TSH and free T4 Why it matters Helps rule out thyroid-related reasons for unexpected weight, energy, or metabolic changes

One recent clinical trial randomized 2301 women in five countries to high dose supplementation (4.0mg folic acid a day) from around 14 weeks gestation to delivery, but did not find a significant effect on rates of developing preeclampsia (Wen 2018)