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doi: 10.1038/s41423-019-0206-4 108 HannaJGoldman-WohlDHamaniYAvrahamIGreenfieldCNatanson-YaronSet al

Nevertheless, there is widespread agreement that until now no pharmacological options are available to tackle the entire spectrum of clinical manifestations observed in PCOS [21]

However, what we produce has a circulating half-life of 2 minutes in our blood stream

Why Storage Rules Exist: The Chemistry Behind Stability Peptide degradation in solution occurs through three primary chemical pathways: hydrolysis (water cleaves the peptide backbone, most rapid at elevated temperature and acidic or alkaline pH), oxidation (methionine, cysteine, and tryptophan side chains react with dissolved oxygen or photocatalytic radicals), and deamidation (asparagine and glutamine residues lose an amide group, producing aspartate or glutamate and altering the peptide's charge and receptor binding)

51 The review authors pointed out that because BPC-157s exact metabolic fate isnt fully known, we should not assume its completely harmless some of its metabolites might trigger harmful oxidative cascades