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10.1016/0009-3084(87)90053-3 135 VatsK.KruglovO.MizesA.SamovichS

Monitoring approach: Establish clear metrics (visual field, OCT, visual acuity), measure every 3-6 months, continue peptides if stable or improving, consider break if stable 12+ months on treatment, resume immediately if decline detected during break, accept ongoing use if clearly beneficial and well-tolerated

Blood Hcy indeed mainly reflects the massive metabolic activity of the liver and provides little information on tissue-specific imbalances, with large variability in Hcy concentration from one organ to another [20]

Martin DN, Uprichard SL