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A very-low-calorie diet A medically supervised 800-calorie ketogenic diet for those with a BMI over 30 (or 27 with health conditions)

Key References Mechanick JI, Butsch WS, Christensen SM, Hamdy O, Li Z, Prado CM, et al

(Simply put, their muscles, bones, and other lean tissues accounted for 53.9% of their body weight.) At the end of the trial, after they had lost 15% of their body weight, their total lean mass increased by three percentage points and accounted for nearly 57% of their total body weight